BDBM600745 US11632953, Compound 1::US11632953, Compound VU041

SMILES FC(F)(F)c1nn(CC(=O)N2CCCc3ccccc23)c2CCCCc12

InChI Key InChIKey=DLAGRCZUELSZFG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 600745   

TargetKir1 channel protein(Yellowfever mosquito)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 1.70E+3nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetAGAP001281-PB(African malaria mosquito)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 2.30E+3nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetAGAP001281-PB(African malaria mosquito)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 2.30E+3nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetAGAP001281-PB(African malaria mosquito)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 2.50E+3nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetInward rectifier potassium channel 2(Human)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 1.13E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetInward rectifier potassium channel 2(Human)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 1.27E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 10(Human)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 3.00E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 3.00E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetInward rectifier potassium channel 13(Human)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 3.00E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 11(Human)
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

US Patent
LigandChemical structure of BindingDB Monomer ID 600745BDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 3.00E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent