BDBM600766 (7S)-5-[4-(trifluoromethyl)phenyl]-3-(2-aminoimidazo[1,2-a]pyridin-6-yl)-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one::US11633395, Example 10

SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nc(N)cn2c1)c1ccc(OC(F)F)cc1

InChI Key InChIKey=IDJMMSBQOGFMNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 600766   

TargetMetabotropic glutamate receptor 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM600766((7S)-5-[4-(trifluoromethyl)phenyl]-3-(2-aminoimida...)
Affinity DataIC50: 302nMAssay Description:Human mGlu2 receptor stable expressing cells were prepared and incubated. Luminescence signals by mGlu2 receptor stimulation were detected with FDSS7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent