BDBM601411 US11634410, Example 21::US11634410, Example 36::[(1R,5S,6R)-3-{3-chloro-5- [(2S,3R)-3-hydroxy-2,3- dimethylazetidin-1-yl]pyridin- 2-yl}-3-azabicyclo[3.1.0]hex- 6-yl]acetic acid

SMILES C[C@@H]1N(C[C@@]1(C)O)c1nc(C(F)F)c(Cl)c(n1)N1C[C@H]2[C@H](CC(O)=O)[C@H]2C1

InChI Key InChIKey=DXMVNXCELGRYED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 601411   

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM601411(US11634410, Example 36 | [(1R,5S,6R)-3-{3-chloro-5...)
Affinity DataIC50: 8.70nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM601411(US11634410, Example 36 | [(1R,5S,6R)-3-{3-chloro-5...)
Affinity DataIC50: 103nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent