BDBM601430 US11634410, Example 38::{(1R,5S,6s)-3-[5-cyano-4- methylpyrrolidin-1-yl)pyridin- 2-yl]-3-azabicyclo[3.1.0]hex- 6-yl}acetic acid

SMILES CC1CCCN1c1nc(cc(C(F)F)c1C#N)N1C[C@H]2[C@H](CC(O)=O)[C@H]2C1

InChI Key InChIKey=FSANLYQNVQEQAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601430   

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM601430(US11634410, Example 38 | {(1R,5S,6s)-3-[5-cyano-4-...)
Affinity DataIC50: 25.3nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent