BDBM601432 US11634410, Example 39::{(1R,5S,6s)-3-[2-(2- (trifluoromethyl)pyrimidin-4- yl]-3-azabicyclo[3.1.0]hex-6- yl}acetic acid

SMILES CC1CCCCN1c1nc(cc(n1)C(F)(F)F)N1C[C@H]2[C@H](CC(O)=O)[C@H]2C1

InChI Key InChIKey=KZPFYVDBEFGFCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601432   

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM601432(US11634410, Example 39 | {(1R,5S,6s)-3-[2-(2- (tri...)
Affinity DataIC50: 24.8nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent