BDBM601614 US11638707, Example 19.

SMILES C[C@H]([C@H]1CN([C@@H](Cc2ccc(Cl)cc2)CO1)C1CCN(CC1)c1nnc(N)[nH]1)n1cccn1

InChI Key InChIKey=WJJNMRBIJWEZGE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 601614   

TargetAcidic mammalian chitinase(Human)
Molecure

US Patent
LigandPNGBDBM601614(US11638707, Example 19.)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC:276). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Molecure

US Patent
LigandPNGBDBM601614(US11638707, Example 19.)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC:276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandPNGBDBM601614(US11638707, Example 19.)
Affinity DataIC50: 6.25E+4nMAssay Description:Fluorescence polarization assay based on the principle of fluorescence polarization where a red-shifted fluorescent tracer is displaced from the hERG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent