BDBM601713 5-((2-((tert- butyl(methyl)amino)meth- yl)benzyl)amino)-3- fluoro-6-methyl-N- (thiazol-4-yl)pyridine-2- sulfonamide::US11639351, Example 34

SMILES CN(Cc1ccccc1CNc1cc(F)c(nc1C)S(=O)(=O)Nc1cscn1)C(C)(C)C

InChI Key InChIKey=SVEAAVZDOOJDPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 601713   

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM601713(US11639351, Example 34 | 5-((2-((tert- butyl(methy...)
Affinity DataIC50: 37nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM601713(US11639351, Example 34 | 5-((2-((tert- butyl(methy...)
Affinity DataIC50: 3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM601713(US11639351, Example 34 | 5-((2-((tert- butyl(methy...)
Affinity DataIC50: 3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent