BDBM601714 3-fluoro-5-((2-fluoro-6- ((isopropyl(methyl)- amino)methyl)benzyl)amino)- 6-methyl-N- (thiazol-4-yl)pyridine-2- sulfonamide::US11639351, Example 35

SMILES CC(C)N(C)Cc1cccc(F)c1CNc1cc(F)c(nc1C)S(=O)(=O)Nc1cscn1

InChI Key InChIKey=XFECQUUPERZKPH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 601714   

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM601714(US11639351, Example 35 | 3-fluoro-5-((2-fluoro-6- ...)
Affinity DataIC50: 24nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM601714(US11639351, Example 35 | 3-fluoro-5-((2-fluoro-6- ...)
Affinity DataIC50: 1.05E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM601714(US11639351, Example 35 | 3-fluoro-5-((2-fluoro-6- ...)
Affinity DataIC50: 3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent