BDBM601725 5-((2-((tert-butyl(methyl)amino)methyl)benzyl)amino)-3-fluoro-N-(isoxazol-3-yl)-6-methylpyridine-2-sulfonamide trifluoroacetic acid salt::US11639351, Example 46

SMILES CN(Cc1ccccc1CNc1cc(F)c(nc1C)S(=O)(=O)Nc1ccon1)C(C)(C)C

InChI Key InChIKey=YPZIMDZWPRPTJU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 601725   

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM601725(US11639351, Example 46 | 5-((2-((tert-butyl(methyl...)
Affinity DataIC50: 1.78E+3nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM601725(US11639351, Example 46 | 5-((2-((tert-butyl(methyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM601725(US11639351, Example 46 | 5-((2-((tert-butyl(methyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent