BDBM601748 US11642348, Compound 111

SMILES CCN(C1CC[C@@H](CC1)N(C)C)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C#CCN1CCOCC1

InChI Key InChIKey=VHEQPBOMYVPYKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601748   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM601748(US11642348, Compound 111)
Affinity DataIC50: 5nMAssay Description:General Procedure for Wild-Type PRC2 Enzyme Assay on Oligonucleosome Substrate. The assays were performed in a buffer consisting of 20 mM bicine (pH=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent