BDBM601780 2-(((S)-4-(6-((5-cyanopyridin-2- yl)methoxy)pyridin-2-yl)-2- methylpiperazin-1-yl)methyl)-1- (((S)-oxetan-2-yl)methyl)-1H- benzo[d]imidazole-6-carboxylic acid::US11643403, Example 1

SMILES C[C@H]1CN(CCN1Cc1nc2ccc(cc2n1C[C@@H]1CCO1)C(O)=O)c1cccc(OCc2ccc(cn2)C#N)n1

InChI Key InChIKey=FJIINAJOFONNDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601780   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601780(2-(((S)-4-(6-((5-cyanopyridin-2- yl)methoxy)pyridi...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
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Date in BDB:
6/11/2023
Entry Details
US Patent