BDBM601906 (S)-2-((4-(6-((5-cyanopyridin-2- yl)methoxy)pyridin-2-yl) piperazin-1-yl)methyl)-1- (oxetan-2-ylmethyl)-1H-benzo [d]imidazole-6-carboxylic acid::US11643403, Example 2

SMILES OC(=O)c1ccc2nc(CN3CCN(CC3)c3cccc(OCc4ccc(cn4)C#N)n3)n(C[C@@H]3CCO3)c2c1

InChI Key InChIKey=MRIJJCCJIRNJBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601906   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601906((S)-2-((4-(6-((5-cyanopyridin-2- yl)methoxy)pyridi...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent