BDBM601922 2-(((S)-4-(6-((4-cyano-2- fluorobenzyl)oxy)pyrazin-2- yl)-2-methylpiperazin-1-yl) methyl)-1-(((S)-oxetan-2-yl) methyl)-1H-benzo[d] imidazole-6-carboxylic acid::US11643403, Example 4

SMILES C[C@H]1CN(CCN1Cc1nc2ccc(cc2n1C[C@@H]1CCO1)C(O)=O)c1cncc(OCc2ccc(cc2F)C#N)n1

InChI Key InChIKey=NXXSOLNVANSEFQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601922   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601922(2-(((S)-4-(6-((4-cyano-2- fluorobenzyl)oxy)pyrazin...)
Affinity DataIC50: 5.58E+4nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent