BDBM601926 2-((4-(3-((4-cyano-2- fluorobenzyl)oxy)phenyl) piperazin-1-yl)methyl)-1-((1- fluorocyclopropyl)methyl)-1H- benzo[d]imidazole-6- carboxylic acid::US11643403, Example 11

SMILES OC(=O)c1ccc2nc(CN3CCN(CC3)c3cccc(OCc4ccc(cc4F)C#N)c3)n(CC3(F)CC3)c2c1

InChI Key InChIKey=PVRXHWBJNNSSTO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601926   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601926(2-((4-(3-((4-cyano-2- fluorobenzyl)oxy)phenyl) pip...)
Affinity DataIC50: 1.85E+4nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent