BDBM601977 US11643417, Ex. No. 10::US11643417, Ex. No. 51

SMILES OC1CCOC(C1)C(F)(F)CN1CCNC(=O)c2oc3ccc(cc3c12)C(F)(F)F

InChI Key InChIKey=FEHCFXDYHWMBNB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 601977   

TargetSerine/threonine-protein kinase pim-1(Human)
Japan Tobacco

US Patent
LigandPNGBDBM601977(US11643417, Ex. No. 10 | US11643417, Ex. No. 51)
Affinity DataKi:  0.0330nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Japan Tobacco

US Patent
LigandPNGBDBM601977(US11643417, Ex. No. 10 | US11643417, Ex. No. 51)
Affinity DataKi:  0.0410nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent