BDBM602146 US11643400, Example 235

SMILES CCOC1CN(C1)C(=O)N[S@@]1(=O)=NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@H](C)[C@@H](C)[C@@H](OC)\C=C\C[C@H](C)C1)c3c2

InChI Key InChIKey=CXDOVWCUMZEBAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602146   

LigandPNGBDBM602146(US11643400, Example 235)
Affinity DataIC50: 0.0350nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent