BDBM602327 (R)-7-chloro-N-(1-(3-(difluoro(1- isopropylpiperidin-4-yl)methyl)-2- fluorophenyl)ethyl)-6-(4- isopropylpiperazin-1-yl)- 2-methylpyrido[2,3-d]pyrimidin- 4-amine::US11648254, Compound 223

SMILES CC(C)N1CCC(CC1)C(F)(F)c1cccc([C@@H](C)Nc2nc(C)nc3nc(Cl)c(cc23)N2CCN(CC2)C(C)C)c1F

InChI Key InChIKey=AKLWXEFGDMAYTM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602327   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602327(US11648254, Compound 223 | (R)-7-chloro-N-(1-(3-(d...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent