BDBM602336 (R)-1-(4-((1-(3-(difluoromethyl)-2- fluorophenyl)ethyl)amino)-2-methyl-7- ((1-methylpiperidin-4-yl)oxy)pyrido [2,3-d]pyrimidin-6-yl)cyclopropane- 1-carbonitrile::US11648254, Compound 232

SMILES C[C@@H](Nc1nc(C)nc2nc(OC3CCN(C)CC3)c(cc12)C1(CC1)C#N)c1cccc(C(F)F)c1F

InChI Key InChIKey=WOUUITCFHZCZIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602336   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602336(US11648254, Compound 232 | (R)-1-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent