BDBM602340 (R)-6-(1-isopropylpiperidin-4-yl)-7- methoxy-2- methyl-N-(1-(2-methyl-3- (trifluoromethyl)phenyl)ethyl)pyrido [2,3-d]pyrimidin-4-amine::US11648254, Compound 236

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(c3C)C(F)(F)F)c2cc1C1CCN(CC1)C(C)C

InChI Key InChIKey=WWFLUGPOYXWLEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602340   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602340(US11648254, Compound 236 | (R)-6-(1-isopropylpiper...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent