BDBM602345 US11648254, Compound 241::tert-butyl (R)-3-((1,1-difluoro-1-(2- fluoro-3-(1- ((6-(4-isopropylpiperazin-1-yl)-7- methoxy-2- methylpyrido[2,3-d]pyrimidin-4- yl)amino)ethyl)phenyl)-2-methylpropan- 2-yl)oxy)azetidine-1-carboxylate

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(c3F)C(F)(F)C(C)(C)OC3CN(C3)C(=O)OC(C)(C)C)c2cc1N1CCN(CC1)C(C)C

InChI Key InChIKey=NJAADANHVGTFIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602345   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602345(US11648254, Compound 241 | tert-butyl (R)-3-((1,1-...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent