BDBM602347 (R)-N-(1-(3-(2-(azetidin-3-yloxy)-1,1- difluoro-2- methylpropyl)-2-fluorophenyl)ethyl)-6- (4-isopropylpiperazin-1-yl)-7-methoxy-2- methylpyrido[2,3-d]pyrimidin-4-amine::US11648254, Compound 243

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(c3F)C(F)(F)C(C)(C)OC3CNC3)c2cc1N1CCN(CC1)C(C)C

InChI Key InChIKey=CWWKAKIHOIQZGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602347   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602347(US11648254, Compound 243 | (R)-N-(1-(3-(2-(azetidi...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent