BDBM602348 (R)-1-(4-((1-(3-(1,1-difluoro-2-hydroxy-2- methylpropyl)-2-fluorophenyl)ethyl) amino)-7-(4- isopropylpiperazin-1-yl)-2- methylpyrido[2,3- d]pyrimidin-6-yl)cyclopropane-1- carbonitrile::US11648254, Compound 244

SMILES CC(C)N1CCN(CC1)c1nc2nc(C)nc(N[C@H](C)c3cccc(c3F)C(F)(F)C(C)(C)O)c2cc1C1(CC1)C#N

InChI Key InChIKey=KGXFVFVNWKUODT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602348   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602348(US11648254, Compound 244 | (R)-1-(4-((1-(3-(1,1-di...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent