BDBM602356 (R)-4-(4-((1-(3-(difluoromethyl)-2- fluorophenyl)ethyl)amino)-7-(2- (dimethylamino)ethoxy)-2- methylpyrido[2,3- d]pyrimidin-6-yl)-1-iminohexahydro- 1l6-thiopyran 1-oxide::US11648254, Compound 250

SMILES C[C@@H](Nc1nc(C)nc2nc(OCCN(C)C)c(cc12)C1CCS(=N)(=O)CC1)c1cccc(C(F)F)c1F

InChI Key InChIKey=RJDFEAYZTSXTPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602356   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602356(US11648254, Compound 250 | (R)-4-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent