BDBM602365 1-(7-chloro-4-(((R)-1-(3-((S)-1,1- difluoro-2-hydroxypropyl)-2- fluorophenyl)ethyl)amino)-2- methylpyrido[2,3-d]pyrimidin-6- yl)cyclopropane-1-carbonitrile::US11648254, Compound 258

SMILES C[C@H](O)C(F)(F)c1cccc([C@@H](C)Nc2nc(C)nc3nc(Cl)c(cc23)C2(CC2)C#N)c1F

InChI Key InChIKey=XQDCQIQXBLMMCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602365   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602365(US11648254, Compound 258 | 1-(7-chloro-4-(((R)-1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent