BDBM602369 (R)-4-(7-chloro-4-((1-(3-(difluoromethyl)- 2-fluorophenyl)ethyl)amino)pyrido [2,3-d]pyrimidin- 6-yl)thiomorpholine 1,1-dioxide::US11648254, Compound 261

SMILES C[C@@H](Nc1ncnc2nc(Cl)c(cc12)N1CCS(=O)(=O)CC1)c1cccc(C(F)F)c1F

InChI Key InChIKey=PUZGTJGIEYCOLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602369   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602369(US11648254, Compound 261 | (R)-4-(7-chloro-4-((1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent