BDBM602370 (R)-4-(7-chloro-4-((1-(2-fluoro-3- (trifluoromethyl)phenyl)ethyl)amino)- 2-methylpyrido[2,3-d]pyrimidin-6- yl)tetrahydro-2H- thiopyran 1,1-dioxide::US11648254, Compound 262

SMILES C[C@@H](Nc1nc(C)nc2nc(Cl)c(cc12)C1CCS(=O)(=O)CC1)c1cccc(c1F)C(F)(F)F

InChI Key InChIKey=DYVKBRKYVDJUOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602370   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602370(US11648254, Compound 262 | (R)-4-(7-chloro-4-((1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent