BDBM602372 1-(4-(((R)-1-(3-((R)-1,1-difluoro-2- hydroxypropyl)phenyl)ethyl)amino)-7- methoxypyrido[2,3-d]pyrimidin-6- yl)cyclopropane-1-carbonitrile::US11648254, Compound 264

SMILES COc1nc2ncnc(N[C@H](C)c3cccc(c3)C(F)(F)[C@@H](C)O)c2cc1C1(CC1)C#N

InChI Key InChIKey=WOYHBCUQACAFMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602372   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602372(US11648254, Compound 264 | 1-(4-(((R)-1-(3-((R)-1,...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent