BDBM602373 1-(7-chloro-4-(((R)-1-(3-((S)-1,1- difluoro-2-hydroxypropyl)phenyl)ethyl) amino)pyrido[2,3-d]pyrimidin-6-yl) cyclopropane-1-carbonitrile::US11648254, Compound 265

SMILES C[C@H](O)C(F)(F)c1cccc(c1)[C@@H](C)Nc1ncnc2nc(Cl)c(cc12)C1(CC1)C#N

InChI Key InChIKey=YSTICCMVFGMDEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602373   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602373(US11648254, Compound 265 | 1-(7-chloro-4-(((R)-1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent