BDBM602377 (R)-7-chloro-N-(1-(3-(difluoro(1- isopropylpiperidin-4- yl)methyl)phenyl)ethyl)-6-(1- isopropylpiperidin-4-yl)-2- methylpyrido[2,3-d] pyrimidin-4-amine::US11648254, Compound 269

SMILES CC(C)N1CCC(CC1)c1cc2c(N[C@H](C)c3cccc(c3)C(F)(F)C3CCN(CC3)C(C)C)nc(C)nc2nc1Cl

InChI Key InChIKey=SXNJGCDZEWOHME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602377   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602377(US11648254, Compound 269 | (R)-7-chloro-N-(1-(3-(d...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent