BDBM602378 1-(4-(((R)-1-(3-(difluoromethyl)-2- fluorophenyl)ethyl)amino)-7-methoxy- 2-(((R)-1- methylpyrrolidin-2-yl)methoxy)pyrido [2,3-d]pyrimidin-6-yl)cyclopropane-1- carbonitrile::US11648254, Compound 270

SMILES COc1nc2nc(OC[C@H]3CCCN3C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1C1(CC1)C#N

InChI Key InChIKey=YSOZVDMAXOAVGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602378   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602378(US11648254, Compound 270 | 1-(4-(((R)-1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent