BDBM602379 (R)-4-(4-((1-(3-(2-(2- (dimethylamino)ethoxy)-1,1- difluoroethyl)-2-fluorophenyl)ethyl) amino)-7-methoxy-2-methylpyrido [2,3-d]pyrimidin-6-yl)thiomorpholine 1,1-dioxide::US11648254, Compound 271

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(c3F)C(F)(F)COCCN(C)C)c2cc1N1CCS(=O)(=O)CC1

InChI Key InChIKey=IJMQFNGDGOBXQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602379   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602379(US11648254, Compound 271 | (R)-4-(4-((1-(3-(2-(2- ...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent