BDBM602380 (R)-4-(4-((1-(3-(difluoro(1- methylazetidin-3- yl)methyl)phenyl)ethyl)amino)-7- methoxy-2- methylpyrido[2,3-d]pyrimidin-6- yl)thiomorpholine 1,1-dioxide::US11648254, Compound 272

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(c3)C(F)(F)C3CN(C)C3)c2cc1N1CCS(=O)(=O)CC1

InChI Key InChIKey=ILDDJXUFFBNXKR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602380   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602380(US11648254, Compound 272 | (R)-4-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent