BDBM602381 (R)-1,1-difluoro-1-(2-fluoro-3-(1-((6- (4-isopropylpiperazin-1-yl)-7- methoxypyrido[2,3-d] pyrimidin-4-yl)amino)ethyl)phenyl)- 2-methylpropan-2-ol::US11648254, Compound 273

SMILES COc1nc2ncnc(N[C@H](C)c3cccc(c3F)C(F)(F)C(C)(C)O)c2cc1N1CCN(CC1)C(C)C

InChI Key InChIKey=XNSRJFXPVNCHFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602381   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602381(US11648254, Compound 273 | (R)-1,1-difluoro-1-(2-f...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent