BDBM602384 (R)-1-(4-((1-(3-(difluoromethyl)-2- fluorophenyl)ethyl)amino)-2-ethynyl-7- methoxypyrido[2,3-d]pyrimidin-6- yl)cyclopropane-1-carbonitrile::US11648254, Compound 276

SMILES COc1nc2nc(nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1C1(CC1)C#N)C#C

InChI Key InChIKey=IGIKXYJAEYKLHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602384   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602384(US11648254, Compound 276 | (R)-1-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent