BDBM602392 (R)-1-(4-((1-(3-(difluoro(1- isopropylazetidin-3- yl)methyl)-2-fluorophenyl)ethyl)amino)- 7-methoxy-2-methylpyrido[2,3-d] pyrimidin-6-yl)cyclopropane-1- carbonitrile::US11648254, Compound 284

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(c3F)C(F)(F)C3CN(C3)C(C)C)c2cc1C1(CC1)C#N

InChI Key InChIKey=VBIJHXAKRZWOKJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602392   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602392(US11648254, Compound 284 | (R)-1-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent