BDBM602704 2-[1-(6-Fluoro-2-isoindolin-2-yl-3-methyl-4-oxo-chromen-8-yl)ethylamino]benzoic acid::US11649227, Example 324::US20230286960, Example 324

SMILES C[C@H](Nc1ccccc1C(O)=O)c1cc(F)cc2c1oc(N1Cc3ccccc3C1)c(C)c2=O

InChI Key InChIKey=RVLPNBBYQFHHRK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 602704   

LigandPNGBDBM602704(US11649227, Example 324 | 2-[1-(6-Fluoro-2-isoindo...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

LigandPNGBDBM602704(US11649227, Example 324 | 2-[1-(6-Fluoro-2-isoindo...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

LigandPNGBDBM602704(US11649227, Example 324 | 2-[1-(6-Fluoro-2-isoindo...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

LigandPNGBDBM602704(US11649227, Example 324 | 2-[1-(6-Fluoro-2-isoindo...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent