BDBM602738 (5Z)-5-[[1-(2-methoxyphenyl)pyrazol-4-yl]methylene]-2-thioxo-thiazolidin-4-one::US11649231, Example 1-30

SMILES COc1ccccc1-n1cc(\C=C2/SC(=S)NC2=O)cn1

InChI Key InChIKey=GMUDISZWGABUOF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602738   

TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602738(US11649231, Example 1-30 | (5Z)-5-[[1-(2-methoxyph...)
Affinity DataIC50: 94.2nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent