BDBM602739 (5Z)-5-[[1-(2-pyridyl)pyrazol-4-yl]methylene]-2-thioxo-thiazolidin-4-one::US11649231, Example 1-33

SMILES O=C1NC(=S)S\C1=C/c1cnn(c1)-c1ccccn1

InChI Key InChIKey=KLTBLEIMRJDBBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602739   

TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602739(US11649231, Example 1-33 | (5Z)-5-[[1-(2-pyridyl)p...)
Affinity DataIC50: 89.6nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
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Date in BDB:
6/19/2023
Entry Details
US Patent