BDBM602875 3-{4-[8-amino-5-(4-aminocyclohex-1-en-1-yl)-3-methylimidazo[1,5-a]pyrazin-1-yl]naphthalen-1-yl}-1-(3-fluorophenyl)urea::US11649237, Example 97

SMILES Cc1nc(-c2ccc(NC(=O)Nc3cccc(F)c3)c3ccccc23)c2c(N)ncc(C3=CCC(N)CC3)n12

InChI Key InChIKey=UVPHVRIJYTUQCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602875   

LigandPNGBDBM602875(US11649237, Example 97 | 3-{4-[8-amino-5-(4-aminoc...)
Affinity DataIC50: 8nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent