BDBM602902 1-(5-(8-amino-3-isopropyl-5-(4-(methylamino)cyclohex-1-en-1-yl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea::US11649237, Example 124

SMILES CNC1CCC(=CC1)c1cnc(N)c2c(nc(C(C)C)n12)-c1cccc2c(NC(=O)Nc3cccc(c3)C(F)(F)F)cccc12

InChI Key InChIKey=SAIOOAGKPSXHNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602902   

LigandPNGBDBM602902(US11649237, Example 124 | 1-(5-(8-amino-3-isopropy...)
Affinity DataIC50: 7nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
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Date in BDB:
6/19/2023
Entry Details
US Patent