BDBM602904 1-(4-(8-amino-3-ethyl-5-(4-(methylamino)cyclohex-1-en-1-yl)imidazo[1,5-a]pyrazin-1-yl)-3-fluorophenyl)-3-(3-fluorophenyl)urea::US11649237, Example 126

SMILES CCc1nc(-c2ccc(NC(=O)Nc3cccc(F)c3)cc2F)c2c(N)ncc(C3=CCC(CC3)NC)n12

InChI Key InChIKey=XNIWEMDQSZRIIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602904   

LigandPNGBDBM602904(US11649237, Example 126 | 1-(4-(8-amino-3-ethyl-5-...)
Affinity DataIC50: 1nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent