BDBM602906 1-(5-(8-amino-3-isopropyl-5-(4-(methylamino)cyclohex-1-en-1-yl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)urea::US11649237, Example 128

SMILES CNC1CCC(=CC1)c1cnc(N)c2c(nc(C(C)C)n12)-c1cccc2c(NC(=O)Nc3ccc4OCCOc4c3)cccc12

InChI Key InChIKey=ATNLCTJLIKBARM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602906   

LigandPNGBDBM602906(US11649237, Example 128 | 1-(5-(8-amino-3-isopropy...)
Affinity DataIC50: 4nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent