BDBM603963 US11655254, Compound 2::US20230382916, Compound 2

SMILES C[C@H]1CN(C[C@@H](C)N1c1ccc(Nc2cc(cn(C)c2=O)-c2ccnc(c2CO)-n2ccn3c4CC(C)(C)Cc4cc3c2=O)nc1)C1COC1

InChI Key InChIKey=MKOCXBGRGYGWAO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 603963   

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM603963(US11655254, Compound 2 | US20230382916, Compound 2)
Affinity DataIC50: 7nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)-based, coupled-enzyme format and is based on the differential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM603963(US11655254, Compound 2 | US20230382916, Compound 2)
Affinity DataIC50: 7nMAssay Description:1. Reagents and Materials: BTK recombinant protein: Invitrogen, Cat #PV3363;Z′-LYTE kinase test kit-tyrosine 1 peptide: Invitrogen, Cat #PV3190...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent