BDBM604604 ((2S,2'S)-1,1'-(4-((1-(3,4,5-trimethoxyphenyl)-1H-imidazol-4-yl)amino)quinazoline-2,7-diyl)bis(pyrrolidine-2,1-diyl))dimethanol::US11661426, Compound 269b::US11661426, Compound 306a

SMILES COc1cc(cc(OC)c1OC)-n1cnc(Nc2nc(nc3cc(ccc23)C2CCCN2CO)C2CCCN2CO)c1

InChI Key InChIKey=WWRQYRPMFSIFNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 604604   

TargetActivin receptor type-1(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM604604(US11661426, Compound 269b | ((2S,2'S)-1,1'-(4-((1-...)
Affinity DataIC50: 100nMAssay Description:Biochemical assays to measure the inhibitory effects of the compounds were performed by ThermoFisher Scientific (Life Technologies). ALK2 inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM604604(US11661426, Compound 269b | ((2S,2'S)-1,1'-(4-((1-...)
Affinity DataIC50: 100nMAssay Description:Biochemical assays to measure the inhibitory effects of the compounds were performed by ThermoFisher Scientific (Life Technologies). ALK2 inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent