BDBM604605 (S)-5-(hydroxymethyl)-1-(4-((1-(3,4,5-trimethoxyphenyl)-1H-imidazol-4-yl)amino)furo[3,2-d]pyrimidin-2-yl)pyrrolidin-2-one::US11661426, Compound 270a

SMILES COc1cc(cc(OC)c1OC)-n1cnc(Nc2nc(nc3ccoc23)N2[C@H](CO)CCC2=O)c1

InChI Key InChIKey=FEWLOMNANCEBID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604605   

TargetActivin receptor type-1(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM604605(US11661426, Compound 270a | (S)-5-(hydroxymethyl)-...)
Affinity DataIC50: 100nMAssay Description:Biochemical assays to measure the inhibitory effects of the compounds were performed by ThermoFisher Scientific (Life Technologies). ALK2 inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent