BDBM604615 (S)-methyl 5-(4-((4-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrrolo[2,1-f][1,2,4]triazin-2-yl)amino)-1H-imidazol-1-yl)-2,3-dimethoxybenzoate::US11661426, Compound 355a

SMILES COC(=O)c1cc(cc(OC)c1OC)-n1cnc(Nc2nc(N3CCC[C@H]3CO)c3cccn3n2)c1

InChI Key InChIKey=NDKFCHPNIUGGMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604615   

TargetActivin receptor type-1(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM604615(US11661426, Compound 355a | (S)-methyl 5-(4-((4-(2...)
Affinity DataIC50: 100nMAssay Description:Biochemical assays to measure the inhibitory effects of the compounds were performed by ThermoFisher Scientific (Life Technologies). ALK2 inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent