BDBM604622 (R)-(1-(2-(1-(3,4,5-trimethoxyphenyl)-1H-imidazol-4-ylamino)pyrrolo[2,1-f][1,2,4]triazin-4-yl)pyrrolidin-3-yl)methanol::US11661426, Compound 283b

SMILES COc1cc(cc(OC)c1OC)-n1cnc(Nc2nc(N3CC[C@@H](CO)C3)c3cccn3n2)c1

InChI Key InChIKey=QHZZFRIHTQSOQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604622   

TargetActivin receptor type-1(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM604622(US11661426, Compound 283b | (R)-(1-(2-(1-(3,4,5-tr...)
Affinity DataIC50: 100nMAssay Description:Biochemical assays to measure the inhibitory effects of the compounds were performed by ThermoFisher Scientific (Life Technologies). ALK2 inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent