BDBM604883 N-(5-Cyano-4-((1-(methoxymethyl))cyclopropyl)amino)pyridin-2-yl)-7-formyl-6-((3-carbonylmorpholino) methyl)-3,4-dihydro-1,8-naphthyridin-1(2H)-carboxamide::US11667631, Example 11

SMILES COCC1(CC1)Nc1cc(NC(=O)N2CCCc3cc(CN4CCOCC4=O)c(C=O)nc23)ncc1C#N

InChI Key InChIKey=WXAXBCBMMXAABN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 604883   

TargetFibroblast growth factor receptor 4(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604883(N-(5-Cyano-4-((1-(methoxymethyl))cyclopropyl)amino...)
Affinity DataIC50: 1.77nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604883(N-(5-Cyano-4-((1-(methoxymethyl))cyclopropyl)amino...)
Affinity DataIC50: 1.00E+4nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR1 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent