BDBM604885 N-(5-Cyano-4-(((cis)-2-methoxycyclopentyl)amino)pyridin-2-yl)-7-formyl-6-((3-carbonylmorpholino) methyl)-3,4-dihydro-1,8-naphthyridin-1(2H)-carboxamide::US11667631, Example 15

SMILES CO[C@H]1CCCC1Nc1cc(NC(=O)N2CCCc3cc(CN4CCOCC4=O)c(C=O)nc23)ncc1C#N

InChI Key InChIKey=ZOFBUJODBDPIBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 604885   

TargetFibroblast growth factor receptor 4(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604885(N-(5-Cyano-4-(((cis)-2-methoxycyclopentyl)amino)py...)
Affinity DataIC50: 3.69nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604885(N-(5-Cyano-4-(((cis)-2-methoxycyclopentyl)amino)py...)
Affinity DataIC50: 1.00E+4nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR1 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent