BDBM604907 N-(5-Cyano-4-(((3,4)-trans-4-methoxytetrahydrofuran-3-yl)oxy)pyridin-2-yl)-7-formyl -6-(((S)-4-methyl-2-carbonyloxazolidin-3-yl)methyl)-3,4-dihydro-1,8-naphthyridin -1(2H)-carboxamide::US11667631, Example 47

SMILES CO[C@H]1COCC1Oc1cc(NC(=O)N2CCCc3cc(CN4[C@@H](C)COC4=O)c(C=O)nc23)ncc1C#N

InChI Key InChIKey=XVBTUTLYDLCYKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 604907   

TargetFibroblast growth factor receptor 4(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604907(N-(5-Cyano-4-(((3,4)-trans-4-methoxytetrahydrofura...)
Affinity DataIC50: 4.95nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604907(N-(5-Cyano-4-(((3,4)-trans-4-methoxytetrahydrofura...)
Affinity DataIC50: 1.00E+4nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR1 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent